Automatic creation of a genetic network for the lac operon from observed data by means of genetic programming

Created by W.Langdon from gp-bibliography.bib Revision:1.7917

@InProceedings{lanza:2000:ICSB,

• author = "Guido Lanza and William Mydlowec and John R. Koza",
• title = "Automatic creation of a genetic network for the lac operon from observed data by means of genetic programming",
• booktitle = "First International Conference on Systems Biology (ICSB)",
• year = "2000",
• address = "Tokyo",
• month = "14-16 " # nov,
• organisation = "Japan Society for Bioinformatics",
• keywords = "genetic algorithms, genetic programming, Biology, genetic networks, reverse engineering, lac operon",
• URL = "http://www.genetic-programming.com/jkpdf/icsb2000geneticnetwork.pdf",
• abstract = "This paper demonstrates that it is possible to use genetic programming to automatically create (reverse engineer) a computer program representing the logic underlying the genetic network for the expression level of the lac operon (composed of the Z, Y, and A genes) as measured by its mRNA. Genetic programming starts with observed time-domain expression levels of two genes (REPRESSOR or CAP) and the concentrations of two substances (GLUCOSE or LACTOSE) and automatically creates both a topological arrangement of conditional and comparative functions as well as all necessary numerical parameters of a genetic network whose behavior matches observed time-domain data.",
• notes = "ICSB-2000 8 Feb 2001 ghostview and our printers barf at icsb2000gn.ps population size 10,000",

}

Genetic Programming entries for Guido Lanza William J Mydlowec John Koza

Citations