- author = "Nesrin Seyhan and Ayse G. Canseven and Goknur Guler and Arin Tomruk and Arzu Firlarer",
- title = "Cellular enzymatic activity and free radical formation in various tissues under static and {ELF} electric and magnetic field exposure",
- booktitle = "Non-Thermal Effects and Mechanisms of Interaction Between Electromagnetic Fields and Living Matter",
- publisher = "Bernardino Ramazzini Institute, National Institute for the Study and Control of Cancer and Environmental Diseases",
- year = "2010",
- editor = "Livio Giuliani and Morando Soffritti",
- pages = "157--175",
- address = "Bologna, Italy",
- note = "An ICEMS Monograph",
- keywords = "genetic algorithms, genetic programming, ANN, Static Electric Field, ELF Electric Field, Magnetic Field, free radicals, antioxidant enzymes, electrolytes, hydroxyproline, Natural Killer cell, invivo EMF",
- isbn13 = "9788862611664",
-
URL = "
http://www.teslabel.be/PDF/ICEMS_Monograph_2010.pdf",
-
URL = "
https://www.emf-portal.org/en/article/18890",
-
URL = "https://www.medicalinformation.it/non-thermal-effects-and-mechanisms-of-interaction-between-electromagnetic-fields-and-living-matter-an-icems-monograph.html",
- size = "29 pages",
- abstract = "Biological effects of static electric and 50-Hz electric (E) and magnetic (B) fields with intensities similar to occupational exposure have been analysed at the Bioelectromagnetic Laboratory of Biophysics Department in the Medical Faculty of Gazi University for more than 25 years. A principal aim of this review is to evaluate the results of our in vivo studies. Static electric field in the range of 0.3-1.9 kV/m (0.3, 0.6, 0.8, 0.9, 1.35, 1.8, 1.9 kV/m) and ELF electric field in the range of 1.35-12 kV/m (1.35, 2, 2.5, 3, 3.5, 4, 4.5, 5, 12 kV/m) were applied to lab animals, directions (vertical and horizontal) and exposure periods (4-8 h/day, for 1, 3, 5, 7, 10 days). ELF magnetic fields were also applied with intensities of 1, 1.5, 2, and 3 mT. Magnetic field exposure periods were 4 h/day for 4, 5 or 7 days and 8 h/day for 5 days. Under the above exposure conditions, cellular enzymatic activities (SOD, GSH-Px, MPO, CAT, ADA and XO) and free radicals (MDA and NOx) were analyzed in the plasma, serum and in the tissues of skin, liver, lung, kidney, brain, spleen and testis. Plasma and brain electrolytes such as Na + , Ca++ , Mg++ , Zn++ and K+ were also studied. Natural Killer cell activity and hydro-xyproline content were examined in the skin, brain, lung, spleen and testis tissues under ELF electric and magnetic fields. In addition, Genetic Programming and Neural Network of those tissues were also studied. The results of this study indicated that the changes in lipid peroxidation level (TBARS) and antioxidant enzyme activity (SOD) induced by 50 Hz E-field exposure are higher than those induced by static field. Cellular alterations induced by electromagnetic fields may influence the biochemical reactions in the cell, changing both biochemical parameters and enzyme activities in serum. Our in vivo studies showed that biological responses of plasma and serum were observed to be differentiated under 50 Hz E-field. We observed that 50 Hz ELF E-field seems to be more effective on plasma than on serum. Power frequency (50 Hz/60 Hz) magnetic fields (MFs) can also affect biological systems by activating secondary chemicals such as radicals. ELF EMF has been thought to prolong the life of free radicals and can act as a promoter or co-promoter of cancer. Therefore, ELF MF was classified as a possible human carcinogen by The International Agency for Research on Cancer-IARC. In the study, the changes in free radical levels (MDA, NO), antioxidant enzymes (GSH, MPO) and in electrolytes concentrations of various tissues (brain, heart, lung, liver, kidney, plasma) were observed under 50 Hz magnetic fields exposure in different exposure durations. In the light of our results, it can be interpreted that magnitude and exposure durations of electric and magnetic fields may play crucial role in both formation of free radicals and biochemical reactions mediated by free radicals within tissues.",
-
notes = "'The GP model contributes an analytical expression in
the form of an interpolation formula that will enable
other researchers in this field to determine changes in
hydroxyproline contents of wound, MDA level, and MPO
activity without further experiments and waste of
animals 84, \cite{Tohumoglu:2007:CMPB} '
Gazi University, Faculty of Medicine, Department of Biophysics
Gazi Non-Ionizing Radiation Protection Center, GNRP, Ankara, Turkey
Cover says {"}European Journal of Oncology Library Vol. 5{"}
FEMU ID: 18890
Mattioli 1885.
Published 2011?",
