- author = "Markus Brameier and Andrea Krings and Robert M. MacCallum",
- title = "{NucPred} Predicting nuclear localization of proteins",
- journal = "Bioinformatics",
- year = "2007",
- volume = "23",
- number = "9",
- pages = "1159--1160",
- keywords = "genetic algorithms, genetic programming",
-
DOI = "
doi:10.1093/bioinformatics/btm066",
- size = "2 pages",
-
abstract = "NucPred analyses patterns in eukaryotic protein
sequences and predicts if a protein spends at least
some time in the nucleus or no time at all. Subcellular
location of proteins represents functional information,
which is important for understanding protein
interactions, for the diagnosis of human diseases and
for drug discovery. NucPred is a novel web tool based
on regular expression matching and multiple program
classifiers induced by genetic programming. A
likelihood score is derived from the programs for each
input sequence and each residue position. Different
forms of visualisation are provided to assist the
detection of nuclear localisation signals (NLSs). The
NucPred server also provides access to additional
sources of biological information (real and predicted)
for a better validation and interpretation of
results.
Availability: The web interface to the NucPred tool is provided at http://www.sbc.su.se/~maccallr/nucpred. In addition, the Perl code is made freely available under the GNU Public Licence (GPL) for simple incorporation into other tools and web servers.",
-
notes = "PMID: 17332022 [PubMed - indexed for MEDLINE]
A few lines in Mutlu Dogruel, Doctor of Philosophy, January 2008 ftp://ftp.sanger.ac.uk/pub/resources/theses/dogruel/chapter4.pdf",
