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Disease Modeling Using Evolved Discriminate Function

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Book cover Genetic Programming (EuroGP 2003)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 2610))

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Abstract

Precocious diagnosis increases the survival time and patient quality of life. It is a binary classification, exhaustively studied in the literature. This paper innovates proposing the application of genetic programming to obtain a discriminate function. This function contains the disease dynamics used to classify the patients with as little false negative diagnosis as possible. If its value is greater than zero then it means that the patient is ill, otherwise healthy. A graphical representation is proposed to show the influence of each dataset attribute in the discriminate function. The experiment deals with Breast Cancer and Thrombosis & Collagen diseases diagnosis. The main conclusion is that the discriminate function is able to classify the patient using numerical clinical data, and the graphical representation displays patterns that allow understanding of the model.

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Author information

Authors and Affiliations

  1. Department of Electronic & Computer Engineering, Brunel University, UB8 3PH, Uxbridge, Middlesex

    James Cunha Werner & Tatiana Kalganova

Authors
  1. James Cunha Werner
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  2. Tatiana Kalganova
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Editor information

Editors and Affiliations

  1. Computer Science and Information Systems, University of Limerick, Limerick, Ireland

    Conor Ryan

  2. Department of Computer Science, University of Idaho, 83844-1010, Moscow, ID, USA

    Terence Soule

  3. Department of Computer Science, Free University of Amsterdam, 1081, HV Amsterdam, The Netherlands

    Maarten Keijzer

  4. Department of Computer Science, University of Essex, Wivenhoe Park, CO4 3SQ, Colchester, UK

    Edward Tsang  & Riccardo Poli  & 

  5. Department of Computer Science, University of Coimbra, Polo II, Pinhal Marrocos, 3030-290, Coimbra, Portugal

    Ernesto Costa

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© 2003 Springer-Verlag Berlin Heidelberg

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Werner, J.C., Kalganova, T. (2003). Disease Modeling Using Evolved Discriminate Function. In: Ryan, C., Soule, T., Keijzer, M., Tsang, E., Poli, R., Costa, E. (eds) Genetic Programming. EuroGP 2003. Lecture Notes in Computer Science, vol 2610. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-36599-0_44

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  • DOI: https://doi.org/10.1007/3-540-36599-0_44

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-00971-9

  • Online ISBN: 978-3-540-36599-0

  • eBook Packages: Springer Book Archive

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